Tenofovir Alafenamide

TAF Intermediates; Tenofovir Alafenamide(GS-7340); GS7340/GS7340; GS-7340 Tenofovir alafenamide; GS-7340-03; L-Alanine,N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-,1-methylethylester

Tenofovir Alafenamide

CAS:379270-37-8

Chemical Formula:C21H29N6O5P

Molecular Weight:476.47

Availability: R&D; Commercialization

Tenofovir Alafenamide

Tenofovir Alafenamide

⬤ CAS No.379270-37-8

⬤ Packaging type:20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging

Product Name Tenofovir Alafenamide
CAS No. 379270-37-8
Chemical Formula C21H29N6O5P
Molecular Weight 476.47
EINECS 1592732-453-0
Related Categories Intermediates; Pharmaceutical raw materials
Melting Point >119°C (dec.)
Boiling Point 640.4±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
Acidity Coefficient (pKa) 4.21±0.10(Predicted)
Storage Conditions 2-8°C(protect from light)
Solubility Soluble in chloroform (a little), DMSO (a little), methanol (a little)
Form Solid
Color White to off-white
Stability Hygroscopicity
InChIKey LDEKQSIMHVQZJK-QTJFZWIYNA-N
Biological Activity Tenofovir alafenamide is a new type of nucleotide reverse transcriptase inhibitor.
Application Tenofovir alafenamide is a prodrug of tenofovir (T018500), a reverse transcriptase inhibitor used to treat HIV and hepatitis B.

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June 15, 2023

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