Sulbenicillin sodium

Sulfobenzylpenicillin; sulfocillin; alpha-sulfobenzylpenicillin disodium; sulpelin;
 SULBENICILLIN DISODIUM SALT;
Sulbenicillin sodium

CAS:28002-18-8

Chemical Formula:C16H16N2Na2O7S2

MW:458.42

Availability: R&D; Commercialization

Sulbenicillin sodium

Sulbenicillin sodium

⬤ CAS No. 28002-18-8

⬤ Packaging type:

20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging

English NameSulbenicillin sodium
CAS No.28002-18-8
Chemical FormulaC16H16N2Na2O7S2
Molecular Weight458.42

 

Related Categories

pharmaceutical intermediates; pharmaceutical antibiotics; medical raw materials; APIs; Raw material; pharmaceutical raw materials; Chemical agent; API intermediates
EINECS248-769-3
Storage conditionsInert atmosphere,Room Temperature
Formsolid
ColorWhite to off-white
Water solubilityWater: 250 mg/mL (545.35 mM)
Adverse reactions 1. Allergic reactions are common, including rash, fever, etc.; Anaphylactic shock is occasional, and once it occurs, it must be rescued on the spot, and treatment measures such as maintaining airway clearance, oxygen inhalation, and adrenaline, glycochemicalbook, and corticosteroids must be given. 2. Nausea, vomiting and other gastrointestinal reactions. 3. Laboratory abnormalities include leukopenia or neutrophilia, transient increase in serum aminotransferases, etc.
Precautions  1. Those who have cross-allergic reactions to penicillin and have a history of penicillin allergy are prohibited. Patients with liver and kidney insufficiency should use with caution. 2. Penicillin sodium skin sensitivity test should be done before use, and positive reactions are prohibited. 3. The sodium salt of this product has a high sodium content, containing 4.37mmol (4.37mEq) of sodium ions per gram, and edema can occur when used in large doses, so it should be noted.
UsesAntibiotics

 

Chemical properties

 

White or light yellow powder, odorless, slightly salty taste, hygroscopic. Very soluble in water, soluble in methanol, slightly soluble in ethanol, very slightly soluble in absolute ethanol, insoluble in acetone, chloroform or benzene.

IndicationsClinically, sulfonicillin sodium can be used for infections caused by Pseudomonas aeruginosa, Escherichia coli, Proteus and other sensitive bacteria, such as purulent inflammation, burns, skin and soft tissue infections, cholecystitis, respiratory and urinary tract infections.

 

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