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Sotorasib (AMG-510)
Sotorasib API;AMG-510 API;Sotorasib cancer treatment;PYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE,6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-[4-METHYL-2-(1-METHYLETHYL)
CAS:2296729-00-3
Chemical Formula:C30H30F2N6O3
Molecular Weight:560.61
Availability: R&D; Commercialization
Sotorasib (AMG-510)
⬤ CAS No.2296729-00-3
⬤ Packaging type：20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| Product Name | Sotorasib |
| CAS No. | 2296729-00-3 |
| Chemical Formula | C30H30F2N6O3 |
| Molecular Weight | 560.61 |
| Related Categories | Inhibitors; Small molecule inhibitors; Raw materials; Anti-tumor drugs; APIs and intermediates |
| Melting point | 730.5±70.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Acidity coefficient (pKa) | 6.52±0.35(Predicted) |
| Storage conditions | Store at -20°C, stored under nitrogen |
| Solubility | DMSO: 100 mg/mL (178.38 mM; requires sonication) |
| Form | Solid |
| Color | White to yellow |
| Water solubility | Water : 33.33 mg/mL (59.46 mM; ultrasonic and adjust pH to 11 with NaOH) |
| InChIKey | NXQKSXLFSAEQCZ-UHFFFAOYSA-N |
| Adverse Reactions | The patients suffered from decreased appetite, diarrhea, fatigue, headache, cough, hot flashes and nausea. No dose-limiting toxicity and drug-related adverse reactions of grade 4 or above were found. |
| Application | Treatment of non-small cell lung cancer. |
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Alexandra Thompson
Exceptional Product Quality
“We have been sourcing pharmaceuticals from Tianming Pharmaceutical for several years now, and their product quality has consistently exceeded our expectations. Each batch undergoes rigorous testing, ensuring we receive only the highest quality products. This reliability has significantly contributed to our trust and satisfaction with their services. Highly recommended!”
June 15, 2023
Ethan Lee
Outstanding Technical Guidance
“The technical guidance provided by Tianming Pharmaceutical’s team has been invaluable to our research and development projects. Their experts are knowledgeable, responsive, and always willing to assist with detailed explanations and support. Their guidance has enabled us to optimize our processes and achieve remarkable results. We couldn’t ask for a better partner.”
June 15, 2023
Sophia Chen
Superior Service Experience
“Our experience with Tianming Pharmaceutical has been nothing short of excellent. Their customer service team is exceptionally responsive and dedicated to meeting our needs. From initial consultation to after-sales support, they have provided seamless, professional service. Their commitment to customer satisfaction is truly commendable.”
June 15, 2023
Lucas Rodriguez
Precise Product Specifications
“Tianming Pharmaceutical has impressed us with their adherence to precise product specifications. Each order is meticulously packaged and delivered exactly as requested, ensuring that we receive products that perfectly meet our requirements. Their attention to detail and commitment to accuracy have made them a trusted supplier for our business.”
June 15, 2023
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