Resmetirom(MGL-3196,VIA-3196)；2-[3,5-DichloroChemicalbook-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazine-6-carbonitrile
CAS:920509-32-6
Chemical Formula:C17H12Cl2N6O4
MW:435.22
Availability: R&D; Commercialization
⬤ CAS No.920509-32-6
⬤ Packaging type：
20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| Product Name | Resmetirom |
| CAS No. | 920509-32-6 |
| Chemical Formula | C17H12Cl2N6O4 |
| Molecular Weight | 435.22 |
| Related Categories | Inhibitors; Pharmaceutical raw materials; API |
| Melting point | 163-165°C |
| Storage conditions | Inert atmosphere,Store in freezer, under -20°C |
| Solubility | DMSO: 59.0 (maximum concentration mg/mL); 135.56 (maximum concentration mM) |
| Form | Crystalline solid |
| Color | Yellow to orange |
| Acidity coefficient (pKa) | 3.96±0.40(Predicted) |
| Density | 1.65±0.1 g/cm3(Predicted) |
| Biological activity | Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β (THR-β) agonist with an EC50 of 0.21 μM and a 28-fold selectivity for THR-β over THR-α. |
| Note | This product is a chemical product and is only used for new drug research and development, process research, chemical intermediate reprocessing, etc. |
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