The Hidden Cost of Switching Pharmaceutical Intermediate Suppliers: A Buyer’s Calculator
Switching intermediate suppliers for 20% lower price? Six hidden costs including bridging studies, regulatory filings, and method revalidation can reach $600K.
Nicotinamide riboside;Pyridinium;Nicotinamide B-D Riboside Chloride
CAS:23111-00-4
Chemical Formula:C11H15ClN2O5
MW:290.70
Availability: R&D; Commercialization
⬤ CAS No.23111-00-4
⬤ Packaging type:
20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging
| Product Name | Nicotinamide Riboside Chloride (NR-CL) |
| CAS Number | 23111-00-4 |
| Molecular Formula | C11H15ClN2O5 |
| Molecular Weight | 290.70 g/mol |
| English Synonyms | Nicotinamide Riboside Chloride, NR-CL, NRC, Nicotinamide Ribose Chloride, 1-ribosylnicotinamide chloride |
| Purity | 98.0% – 99.0% |
| Available Sizes | 100 mg, 500 mg, 1g, 5g, 25g, 100g, 1kg, 10kg, 50kg, 500kg |
| Suppliers | Shandong Tianming Pharmaceutical Group Co., Ltd., etc. |
| Product Name | Nicotinamide Riboside Chloride (NR) |
| CAS Number | 23111-00-4 |
| Hazard Classification | Generally Recognized as Safe (GRAS) for use in dietary supplements, but handle with care as a chemical |
| Hazards | Eye Irritation, Skin Contact, Inhalation, Ingestion |
| Precautions | Handle with care, Store properly, Dispose of responsibly |
| Fire/Explosion Hazard | Non-combustible solid. No specific fire hazard identified |
| Environmental Considerations | Avoid release to the environment. Dispose of in accordance with local regulations |
| Product Name | Nicotinamide Riboside Chloride (NR) |
| CAS Number | 23111-00-4 |
| Molecular Formula | C11H15ClN2O5 |
| Molecular Weight | [Calculated] |
| Purity | ≥99% (Typical) |
| Appearance | White to off-white powder |
| Solubility | Soluble in water, DMSO, ethanol |
| Storage Conditions | Store at room temperature, protected from light and moisture |
| Stability | Stable under recommended storage conditions |
| Analytical Methods | HPLC, NMR, etc. (as used for analysis) |
Exceptional Product Quality
“We have been sourcing pharmaceuticals from Tianming Pharmaceutical for several years now, and their product quality has consistently exceeded our expectations. Each batch undergoes rigorous testing, ensuring we receive only the highest quality products. This reliability has significantly contributed to our trust and satisfaction with their services. Highly recommended!”
June 15, 2023
Outstanding Technical Guidance
“The technical guidance provided by Tianming Pharmaceutical’s team has been invaluable to our research and development projects. Their experts are knowledgeable, responsive, and always willing to assist with detailed explanations and support. Their guidance has enabled us to optimize our processes and achieve remarkable results. We couldn’t ask for a better partner.”
June 15, 2023
Superior Service Experience
“Our experience with Tianming Pharmaceutical has been nothing short of excellent. Their customer service team is exceptionally responsive and dedicated to meeting our needs. From initial consultation to after-sales support, they have provided seamless, professional service. Their commitment to customer satisfaction is truly commendable.”
June 15, 2023
Precise Product Specifications
“Tianming Pharmaceutical has impressed us with their adherence to precise product specifications. Each order is meticulously packaged and delivered exactly as requested, ensuring that we receive products that perfectly meet our requirements. Their attention to detail and commitment to accuracy have made them a trusted supplier for our business.”
June 15, 2023
Switching intermediate suppliers for 20% lower price? Six hidden costs including bridging studies, regulatory filings, and method revalidation can reach $600K.
This guide decodes the seven validation parameters defined in ICH Q2(R2) from an intermediate buyer’s perspective, explains why stability-indicating methods matter for retest dating, and provides six questions buyers should ask suppliers about their analytical methods.
Learn how ICH Q11 starting material rules affect pharmaceutical intermediate sourcing—supplier boundaries, COA red flags, and a practical buyer’s checklist.
Leading provider of high-quality APIs and intermediates. Contact us for innovative solutions and expert support.