LCZ696 intermediate; tert-butyl (R)-(1-([1,1′-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate
CAS:1426129-50-1
Chemical Formula:C20H25NO3
MW:327.42
Availability: R&D; Commercialization
⬤ CAS No.1426129-50-1
⬤ Packaging type：20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| English Name | N-[(1R)-2-[1,1′-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester |
| CAS No. | 1426129-50-1 |
| Chemical Formula | C20H25NO3 |
| Molecular Weight | 327.42 |
Related Categories | LCZ696 intermediate; reference substance-impurity reference substance; medical raw material; antihypertensive; impurity reference substance; LCZ696; LCZ 696 |
| Mol | 1426129-50-1.mol |
| Boiling point | 514.5±50.0 °C(Predicted) |
| Density | 1.103±0.06 g/cm3(Predicted) |
| Storage conditions | 2-8°C |
| Acidity coefficient (pKa) | 11.85±0.46(Predicted) |
| InChIKey | TYQICOFAZDVKMK-GOSISDBHSA-N |
| SMILES | C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1 |
| Product name | N-[(1R)-2-[1,1′-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester |
| Molecular formula | C20H25NO3 |
| Skin contact | Immediately flush with plenty of clean water. |
| Eye contact | Immediately flush with plenty of clean water and seek medical attention. |
| Inhalation | Move to fresh air, seek medical attention immediately if you feel unwell. |
| Ingestion | Do not induce vomiting, seek medical attention immediately. |
| Personal protection | Wear chemical protective clothing, gloves, goggles, etc. |
| Leakage treatment | Use sand, inert absorbent, or other suitable substances to absorb the leaked material and transfer it to a safe container. |
| Environmental protection | Prevent the leaked material from entering the sewer, water bodies, etc. |
| Storage conditions | Store in a dry, cool, well-ventilated place, away from fire and heat sources. |
| Transportation precautions | Comply with relevant transportation regulations and avoid mixing with incompatible materials. |
| Disposal method | Comply with relevant disposal regulations and avoid mixing with incompatible materials. |
| Uses | LCZ696 intermediate is a useful intermediate for the preparation of sabibil (S080900)/valsartan (V095750). |
Applications | LCZ696 intermediate is an intermediate for organic synthesis and pharmaceutical research and development. It is mainly used as an organic intermediate and a pharmaceutical intermediate. It can be used in laboratory research and development processes and chemical pharmaceutical synthesis processes. It can be used for the synthesis of the raw material drug LCZ696. |
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