SODIUM CEFTIOFUR；CEFTIOFUR-D3 SODIUM SALT；Ceftiofur Sodic; ceftiofur sodium salt; naxcel; Third-generation cephalosporin antibiotics
CAS:104010-37-9
Chemical Formula: C₁₉H₁₆N₅NaO₇S₃
MW:547.55
Availability: R&D; Commercialization
⬤ CAS No.104010-37-9
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| English Name | Ceftiofur sodium |
| CAS No. | 104010-37-9 |
| Chemical Formula | C₁₉H₁₆N₅NaO₇S₃ |
| Molecular Weight | 547.55 |
Related Categories | Active Pharmaceutical Ingredients and Intermediates; Antibiotics; Pharmaceutical Intermediates; Intermediates; Veterinary APIs; Small Molecule Inhibitors; The World’s First Third-Generation Cephalosporin Specifically for Poultry and Livestock, Veterinary GMP; Veterinary Medicine Raw Materials |
| EINECS | 680-655-2 |
| Storage conditions | under inert gas (nitrogen or Argon) at 2–8 °C |
| Form | Solid |
| Color | Pale yellow |
| Solubility | Soluble in aqueous solution |
| Melting point | >185°C (dec.) |
| RTECS | XI0367360 |
| Product Name | Ceftiofur Sodium |
| Drug Classification | Third-generation cephalosporin antibiotic |
| Indications | Used in cattle, pigs, horses, and other animals for the treatment of bacterial infections such as respiratory, urinary tract, and skin infections |
| Mechanism of Action | Inhibits bacterial cell wall synthesis, leading to bacterial lysis and death |
| Contraindications | Contraindicated in animals with hypersensitivity to ceftiofur, other cephalosporins, or any component of the formulation |
| Warnings & Precautions | Monitor for hypersensitivity reactions, use with caution in animals with impaired hepatic or renal function, assess for drug interactions, observe withdrawal periods, avoid intrathecal or intraocular administration |
| Adverse Reactions | Includes hypersensitivity reactions, gastrointestinal upset, injection site reactions, hematological abnormalities, neurological symptoms, etc. |
| Dosage & Administration | Dosage varies by animal species and is determined by the veterinarian, can be administered via intramuscular or intravenous injection |
| Storage & Handling | Store at controlled room temperature, in a dry, well-ventilated place, protected from light and moisture, out of reach of children and animals, do not freeze |
| Drug Interactions | May interact with other antibiotics, particularly those with overlapping antibacterial spectra |
| Overdose | Overdose may result in exaggerated adverse reactions, contact a veterinarian immediately if overdose is suspected |
| Disposal | Dispose of unused or expired products and their empty containers according to local hazardous waste disposal regulations |
| Introduction | Cefotaxiofur sodium is the sodium salt of ceftiofur, which belongs to the third-generation cephalosporin class of antibiotics and was first marketed in United States in 1988. The chemical properties are stable, the appearance is light yellow to white crystalline powder, and the aqueous solution has a short storage time, so it should be diluted into a solution before use. |
| Biological activity | Ceftiofurna sodium is a third-generation cephalosporin antibiotic approved for veterinary use. |
| Use | It is an antibiotic used to treat bacterial respiratory tract infections in pigs |
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