The Hidden Cost of Switching Pharmaceutical Intermediate Suppliers: A Buyer’s Calculator
Switching intermediate suppliers for 20% lower price? Six hidden costs including bridging studies, regulatory filings, and method revalidation can reach $600K.
Avibactam sodium salt; NXL-104 sodium; β-lactamase inhibitor API; sodium (1R,2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate
CAS:1192491-61-4
Chemical Formula:C7H10N3NaO6S
Molecular Weight:289.24
Availability: R&D; Commercialization
⬤ CAS No.1192491-61-4
⬤ Packaging type:
20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging
| Product Name | Avibactam sodium |
| CAS No. | 1192491-61-4 |
| Chemical Formula | C7H10N3NaO6S |
| Molecular Weight | 289.24 |
| Related Categories | Anti-bacterial infection API |
| Storage Conditions | Sealed in dry,Room Temperature |
| Melting Point | >208°C (dec.) |
| Solubility | DMSO (slight dissolution), methanol (slight dissolution, heating, sonication), water (slight dissolution, sonication) |
| Form | solid |
| water solubility | H2O: 2mg/mL, clear |
| Color | White to off-white |
| Note | Avibactam sodium is a covalent, reversible β-lactamase (β-lactamase) inhibitor that potently inhibits the β-lactamases TEM-1 and CTX-M-15, with IC50 values of 8 nM and 5 nM, respectively. |
| Application | It is often used in combination with other antibiotics to enhance the bactericidal effect of antibiotics against drug-resistant bacteria. |
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