The Hidden Cost of Switching Pharmaceutical Intermediate Suppliers: A Buyer’s Calculator
Switching intermediate suppliers for 20% lower price? Six hidden costs including bridging studies, regulatory filings, and method revalidation can reach $600K.
(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol; Empagliflozin Intermediate
CAS: 915095-99-7
Chemical Formula:C31H35ClO11
Molecular Weight: 619.06
Availability: R&D; Commercialization
⬤ CAS No. 915095-99-7
⬤ Our Packaging type:
20kg barrel;5kg barrel;1kg bag;500g bag ; Customized Packaging
| Product Name | Acetoxy Empagliflozin |
| CAS No. | 915095-99-7 |
| Chemical Formula | C31H35ClO11 |
| Molecular Weight | 619.06 |
| EINECS | 1592732-453-0 |
| Related Categories | Empagliflozin Intermediate |
| Boiling Point | 673.8±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Note | Non-pharmaceutical, only used for industrial synthesis or research and development |
| Core Drug Synthesis | Key intermediates for Empagliflozin API;Used in the synthesis of SGLT2 inhibitor drugs |
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March 18, 2024
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February 15, 2024
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June 15, 2024
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“Over 5+ years, Tianming has consistently adapted to our evolving needs—whether scaling volumes or supporting custom synthesis projects. Their ethical pricing models and long-term vision make them more than a vendor; they’re integral to our competitive edge.”
April 27, 2024
Switching intermediate suppliers for 20% lower price? Six hidden costs including bridging studies, regulatory filings, and method revalidation can reach $600K.
This guide decodes the seven validation parameters defined in ICH Q2(R2) from an intermediate buyer’s perspective, explains why stability-indicating methods matter for retest dating, and provides six questions buyers should ask suppliers about their analytical methods.
Learn how ICH Q11 starting material rules affect pharmaceutical intermediate sourcing—supplier boundaries, COA red flags, and a practical buyer’s checklist.
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