Ultimate First Article Approval Checklist For A New Supplier
The first commercial batch from a new intermediate supplier is not a formality. Here is the checklist, the five approval outcomes, and how to log the call.
October 21, 2026
(Rac)-Finerenone
4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide；Finerenone Intermediates
CAS:1050477-27-4
Chemical Formula:C21H22N4O3
Molecular Weight:378.42
Availability: R&D; Commercialization
(Rac)-Finerenone
⬤ CAS No.1050477-27-4
⬤ Packaging type：
20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| Product Name | (Rac)-Finerenone |
| CAS No. | 1050477-27-4 |
| Chemical Formula | C21H22N4O3 |
| Molecular Weight | 378.42 |
| EINECS | 810-201-2 |
| Related Categories | Finerenone Intermediate |
| Melting point | 140-142 °C (decomp) |
| Specific rotation | D20 -31.5° (c = 1.2 in water) |
| Storage conditions | 20°C |
| Color | White |
| PH | About 3.0 (50mg/mL in water) |
| Note | This product is strictly designated as a non-pharmaceutical chemical intermediate and must be used exclusively for industrial synthesis purposes |
| Core drug synthesis | Used to synthesize Finerenone API |
| R&D and process optimization | Stereochemical studies;Process scale-up verification |
| Expanding application areas | Development of novel MR antagonists; Research on metabolic diseases |
Customer Reviews
Real customer feedback
Michael Carter
Reliable Global Partner
“Tianming Pharmaceutical has redefined reliability for us. Their ability to deliver high-potency APIs and intermediates under tight deadlines—is unmatched. The team’s transparency in documentation and proactive updates make them a stress-free partner. A true backbone for our operations!”
March 18, 2024
Dr. Sofia Alvarez
Outstanding Technical Guidance
“Few suppliers align so perfectly with EU GMP requirements. Tianming’s commitment to audit-ready quality systems, batch traceability, and purity consistency has streamlined our production processes. Their diligence eliminates regulatory risks—a rare advantage in today’s market.”
February 15, 2024
Rajesh Kapoor
Beyond Supplier, A Solutions Partner
“Tianming’s technical team doesn’t just deliver materials—they solve problems. When we faced stability challenges with a niche compound, their scientists proposed a tailored purity adjustment that saved our project timeline. Their agility transforms obstacles into opportunities.”
June 15, 2024
Emily Zhang
Strategic Growth Ally
“Over 5+ years, Tianming has consistently adapted to our evolving needs—whether scaling volumes or supporting custom synthesis projects. Their ethical pricing models and long-term vision make them more than a vendor; they’re integral to our competitive edge.”
April 27, 2024
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Still Have Questions？
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