TAF Intermediates; Tenofovir Alafenamide(GS-7340); GS7340/GS7340; GS-7340 Tenofovir alafenamide; GS-7340-03; L-Alanine,N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-,1-methylethylester
CAS:379270-37-8
Chemical Formula:C21H29N6O5P
Molecular Weight:476.47
Availability: R&D; Commercialization
⬤ CAS No.379270-37-8
⬤ Packaging type：20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| Product Name | Tenofovir Alafenamide |
| CAS No. | 379270-37-8 |
| Chemical Formula | C21H29N6O5P |
| Molecular Weight | 476.47 |
| EINECS | 1592732-453-0 |
| Related Categories | Intermediates; Pharmaceutical raw materials |
| Melting Point | >119°C (dec.) |
| Boiling Point | 640.4±65.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Acidity Coefficient (pKa) | 4.21±0.10(Predicted) |
| Storage Conditions | 2-8°C(protect from light) |
| Solubility | Soluble in chloroform (a little), DMSO (a little), methanol (a little) |
| Form | Solid |
| Color | White to off-white |
| Stability | Hygroscopicity |
| InChIKey | LDEKQSIMHVQZJK-QTJFZWIYNA-N |
| Biological Activity | Tenofovir alafenamide is a new type of nucleotide reverse transcriptase inhibitor. |
| Application | Tenofovir alafenamide is a prodrug of tenofovir (T018500), a reverse transcriptase inhibitor used to treat HIV and hepatitis B. |
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