Trelagliptin Succinate (SYR-472); SYR 111472 succinate; SYR-472 succinate; SYR-472 Trelagliptin succinat; Trelagliptin succinate (SRY-472)
CAS:1029877-94-8
Chemical Formula:C22H26FN5O6
MW:475.48
Availability: R&D; Commercialization
⬤ CAS No.1029877-94-8
⬤ Packaging type：
20kg barrel；5kg barrel；1kg bag；500g bag ; Customized Packaging
| English Name | Trelagliptin succinate |
| CAS No. | 1029877-94-8 |
| Chemical Formula | C22H26FN5O6 |
| Molecular Weight | 475.48 |
Related Categories | Pharmaceutical APIs; Antihypertensive and Antidiabetic Drugs; Trelagliptin Succinate; APIs; Pharmaceutical Intermediates; Biochemicals; Pharmaceutical Raw Materials |
| Mol | 1029877-94-8.mol |
| Storage conditions | -20°C |
| Form | powder |
| Color | Off-white solid |
| Solubility | Soluble in dimethyl sulfoxide |
| Hazard Classification | Not specifically classified, but generally considered as a pharmaceutical intermediate |
| Precautionary Statements (P-Statements) | P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P270: Do not eat, drink or smoke when using this product. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
| Fire Hazard | Low flammability (as a solid pharmaceutical intermediate) |
| Health Hazards | May cause irritation to skin, eyes, and respiratory system if handled improperly. Consult a physician if ingested or inhaled. |
| Environmental Hazards | May have adverse effects on aquatic life if released into the environment. Dispose of according to local regulations. |
| Storage Conditions | Store in a cool, dry place, away from direct sunlight and heat sources. Keep container tightly closed. |
| Stability and Reactivity | Stable under recommended storage conditions. Incompatible with strong oxidizing agents. |
| First Aid Measures | If skin contact occurs, wash thoroughly with soap and water. If eye contact occurs, flush eyes with water and seek medical attention. If ingested, do not induce vomiting and seek medical attention immediately. |
| Handling and Storage Precautions | Wear appropriate personal protective equipment (PPE) during handling, including chemical-resistant gloves, eye protection, and protective clothing. |
| Indications | For the treatment of type 2 diabetes. |
| Physical and chemical properties | Trelagliptin succinate is white to off-white crystals or crystalline powder, easily soluble in water or dimethyl sulfoxide, slightly soluble in methanol, slightly soluble in ethanol (99.5), tetrahydrofuran or diethylamine, and very slightly soluble in acetonitrile or 2-propanol. |
| Applications | Trelagliptin succinate is a dipeptidyl peptidase IV (DPP-IV) inhibitor that can selectively and continuously inhibit DPP-IV and control blood sugar levels. Clinical trials have shown that the drug has good safety and efficacy, and can effectively control blood sugar levels and improve patients’ medication compliance with a single weekly administration. |
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